BDBM50380144 CHEMBL2010994::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 8
SMILES CC(C)(C)c1cc(=O)[nH]c(SCC(=O)c2ccc(cc2)S(N)(=O)=O)n1
InChI Key InChIKey=OMYTZYUGUKDESE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50380144
Affinity DataKoff: 2.40E+6s-1Assay Description:Binding affinity to human recombinant CA13 assessed as association rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.0100M-1s-1Assay Description:Binding affinity to human recombinant CA13 assessed as dissociation rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.20nMAssay Description:Binding affinity to human recombinant CA13 after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.40nMAssay Description:Binding affinity to human recombinant CA13 by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 37nMAssay Description:Binding affinity to human recombinant carbonic anhydrase-13 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.5nMAssay Description:Binding affinity to human recombinant carbonic anhydrase-13 by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.00580nMAssay Description:Binding affinity to human N-terminal full length His-tagged CA13 (1 to 262 residues) expressed in Escherichia coli BL21(DE3) assessed as intrinsic th...More data for this Ligand-Target Pair
Affinity DataKon: 1.00E-8M-1s-1Assay Description:Binding affinity to human N-terminal full length His-tagged CA13 (1 to 262 residues) expressed in Escherichia coli BL21(DE3) assessed as dissociation...More data for this Ligand-Target Pair
Affinity DataKd: 3.5nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 13 by thermal shift assayMore data for this Ligand-Target Pair